Nearly 1.5 million patients present to US emergency departments annually following head trauma. Headache is a frequent symptom of victims of head trauma. The purpose of this study is to see if an intravenous medication called metoclopramide can improve the symptoms of patients with acute post-traumatic headache.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
160
Metoclopramide 20mg
Diphenhydramine 25mg
100ml normal saline
Montefiore Medical Center
The Bronx, New York, United States
0-10 Pain Scale on Which 0 = no Pain and 10= the Worst Pain Imaginable
Improvement in this 0 to 10 verbal rating scale
Time frame: 1 hour after medication administration
Sustained Headache Relief
Achieving a headache intensity of mild or none in the ED without use of rescue medication and maintaining a level of mild or none. Participants rate their headache as none, mild, moderate, or severe
Time frame: 48 hours after medication administration
Headache Days
Number of days with any headache. Participants report the actual number of days they experienced headache. A "day" begins when they awake for the beginning of daily activities and ends when they go to sleep after completion of daily activities
Time frame: 7 days after ED visit
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