To examine the impact of health determinants at the individual (e.g. health related behaviors) and societal level (e.g. environmental factors, health related policy, quality of health systems) on health outcomes (e.g. death, non-communicable disease development) across a range of socioeconomic and health resource settings. Additional components of this study will examine genetic factors for non-communicable diseases. This will be examined both through a cross sectional component, and prospectively (cohort component).
1. To examine the relationship between societal influences and prevalence of risk factors and chronic noncommunicable diseases. Societal determinants are measured by an index of measures from each of the 4 domains of interest: built environment, food and nutrition policy, psychosocial/socioeconomic factors, and tobacco. 2. To examine the relationship between societal determinants and incidence of chronic noncommunicable disease events (e.g. cardiovascular disease, cancer) and on changes in rates of selected risk factors (e.g. smoking) 3. To examine the relationship between health related behaviors (e.g. diet, physical activity, smoking, alcohol) and health outcomes (e.g. death, non-communicable diseases) 4. The quality of health systems across a diverse range of health resource settings, and how this impacts health outcomes 5. Genetic factors for non-communicable diseases
Study Type
OBSERVATIONAL
Enrollment
200,000
Estudios Clinicos Latinoamerica ECLA
Rosario, Santa Fe Province, Argentina
RECRUITINGIndependent University, Bangladesh
Dhaka, Bangladesh
RECRUITINGDante Pazzanese Institute of Cardiology
São Paulo, Brazil
RECRUITINGSimon Fraser University
Vancouver, British Columbia, Canada
incident cardiovascular disease
cardiovascular death, stroke, myocardial infarction, heart failure
Time frame: mean follow up of 10 years
incident cancer
total and cause specific cancers
Time frame: mean follow up of 10 years
Incident COPD
development of COPD
Time frame: mean follow up of 10 years
Incident Asthma
development of asthma
Time frame: mean follow up of 10 years
Pneumonia
hospitalization for pneumonia
Time frame: mean follow up of 10 years
Respiratory outcomes
change in pulmonary function test
Time frame: mean follow up of 10 years
All Cause Hospitalizations
All cause hospitalizations
Time frame: mean follow up of 10 years
Kidney disease
end stage renal disease, dialysis, transplant, changes in renal function
Time frame: mean follow up of 10 years
All cause and cause specific mortality
death from all causes, and cause specific deaths
Time frame: mean follow up of 10 years
incident diabetes
development of diabetes
Time frame: mean follow up of 10 years
obesity
development of obesity, change in BMI
Time frame: mean follow up of 10 years
hypertension
development of hypertension and changes in blood pressure
Time frame: mean follow up of 10 years
incident injuries
assessing fatal and non-fatal injuries due road traffic accidents and falls
Time frame: mean follow up of 10 years
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Population Health Research Institute
Hamilton, Ontario, Canada
RECRUITINGUniversity of Ottawa
Ottawa, Ontario, Canada
RECRUITINGUniversité Laval Institut universitaire de cardiologie et de pneumologie de Québec
Québec, Quebec, Canada
RECRUITINGUniversidad de La Frontera
Temuco, Chile
RECRUITINGState Key Laboratory of Cardiovascular Disease, Fuwai Hospital
Beijing, China
RECRUITINGFundacion Oftalmologica de Santander - FOSCAL
Floridablanca, Santander Department, Colombia
RECRUITING...and 24 more locations