To find out the safety and efficacy of Optical Coherence Tomography (OCT) in the evaluation and treatment of angiographically borderline coronary artery lesions in a Chinese population, and to compare the effectiveness of OCT versus SPECT in treating such subjects. All the participants included in the study will be those that are found to have borderline coronary artery lesions on coronary angiography, in whom the investigators feel that OCT will be useful to assess whether PCI will be of benefit to the treatment of the lesion pathology, or whether optimal medical therapy is the most appropriate treatment modality. Those participants who declined OCT will be offered SPECT as an alternative method to assess and treat the borderline coronary artery stenosis. It is estimated that OCT guided "PCI or not" has a non-inferiority to SPECT's in the borderline coronary artery stenosis.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
220
OCT is used to assess whether PCI will be of benefit to the treatment of the borderline coronary artery lesions
First Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China
MACEs
The incidence of major adverse cardiac events (MACEs) including death, myocardial infarction, and stent thrombosis.
Time frame: 12 months
TLR
The incidence of target lesion revascularization (TLR)
Time frame: 12 months
Rehospitalization
The incidence of rehospitalization due to cardiac events
Time frame: 12 months
Recurrent angina
The incidence of recurrent angina
Time frame: 12 months
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