The objective of this study is to investigate the use of patient throat gargle as an alternative to throat swabbing for the diagnosis of pharyngitis caused by Group A β-Hemolytic Streptococcus (GABHS) infection, also known as strep throat.
The aim of this study is to procure a detailed quantitative and qualitative analysis of GABHS present in patient throat gargle and to compare various culturing techniques and immunoassay methods for efficient and effective GABHS detection from gargle fluid. During the course of this clinical trial, the following specimen samples will be collected from each participating patient: the patient will first be asked to gargle 10-15 mL of sterile saline to obtain a gargle sample, and then the patient will be subjected to two routine standard throat swabs. These specimen samples will be properly discarded after processing and analysis.
Study Type
OBSERVATIONAL
Enrollment
34
TEREM Ha'Gdud Ha'Ivri Family Clinic
Jerusalem, Israel
Comparative: Method sensitivity to investigate method effectiveness.
Compare sensitivity of each gargle fluid GABHS detection method.
Time frame: Through study completion, about 9 months
Comparative: Method specificity to investigate method effectiveness.
Compare specificity of each gargle fluid GABHS detection method.
Time frame: Through study completion, about 9 months
Quantitative: Average GABHS in gargle.
Average number of total GABHS bacteria collected in throat gargle samples.
Time frame: Through study completion, about 9 months
Quantitative: Minimum GABHS in gargle.
Minimum number of total GABHS bacteria collected in throat gargle samples.
Time frame: Through study completion, about 9 months
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