Determining the Ergogenic Effects of Carb10™ Supplementation on Carbohydrate-Rich and Carbohydrate-Restricted Diets

Texas Woman's University59 enrolled

Overview

The study will examine the performance and body composition effects of ketogenic vs carbohydrate-based diets, determine the carbohydrate tolerance ("carbohydrate threshold") for active individuals on a ketogenic diet, and then, reexamine the performance and body composition effects when the diets are modified with supplemental carbohydrate up to the newly defined "ketogenic threshold."

Participants will be recruited from TWU and the Denton area and grouped in a semi-randomized fashion that considers dietary preferences. They will then undergo baseline testing, begin the diet and training interventions, followed by post-testing (phase 1) and a carbohydrate titration period in the ketogenic diet group (phase 2). In the following academic semester, the training intervention will be repeated with an adjusted dietary carbohydrate level, delivered as a pre-workout supplement, corresponding to Phase 2 (Phase 3). Phase 1 will consist of diets at an energy level estimated by the Mifflin St. Jeor equation adjusted by 1.625 for exercise. The exercise intervention will be a supervised, periodized (daily undulating), 9-week concurrent resistance (3 days/week) and cardiovascular (2 days/week) exercise program designed to improve body composition and performance variables. During phase 2, the ketogenic diet participants will continue exercising with the same program while consuming incrementally greater quantities of carbohydrate pre-workout until the state of ketosis is lost. Phase 3 will be identical to Phase 1, but diets will be modified to include more carbohydrate. As of completing Phase 2, this amount has been determined to be 20g of Carb10 (pea starch).

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

Ketogenic Dieting

Interventions

Carbohydrate Supplement (Carb10)DIETARY_SUPPLEMENT

2 of 4 arms will be supplemented with carbohydrate pre-workout (Carb10, Compound Solutions, Carlsbad, CA)

DietOTHER

2 groups will be on a carbohydrate-based diet (% energy from carbohydrate:fat:protein, 53:24:23) and 2 groups will be on a ketogenic diet (72:5:23)

ExerciseOTHER

All groups will participate in a standardized exercise intervention.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * consistently exercising at least 3 days per week for the past 2 years, participating in both cardiovascular and resistance exercise at least once per week for the past 2 years, reported themselves as healthy, and were willing and able to comply with study protocols Exclusion Criteria: * using tobacco of any form, a history of medical events, reporting any supplement or medication use that may affect study outcomes, regularly consuming \> 7 alcoholic beverages per week, appearing unfit to handle the training program, inability to complete baseline testing, having a BMI \> 35 kg/m2, or becoming \< 80% compliant with training or dietary interventions.

Locations (1)

Texas Woman's University

Denton, Texas, United States

Outcomes

Primary Outcomes

Change in Body Composition

Will be measured as fat and lean soft tissue mass in kg by dual x-ray absorptiometry (DXA)

Time frame: 0 and 10 weeks

Change in Anaerobic Cardiovascular Performance

Will be measured as peak and average power output in Watts during a repeated Wingate sprint test

Time frame: 0 and 10 weeks

Secondary Outcomes

Change in Body Composition

In addition to DXA, body composition will be verified using bioelectric impedance (BIS) estimations of fat-free and fat mass in kg

Time frame: 0 and 10 weeks

Change in Body Water

BIS determined total, intra-, and extra-cellular fluid in Liters

Time frame: 0 and 10 weeks

Change in Cross-sectional Area

B-mode ultrasound determined cross-sectional area of the rectus femoris in cm squared

Time frame: 0 and 10 weeks

Change in Muscle Thickness

B-mode ultrasound determined combined thickness of the vastus lateralis and vastus medius in cm

Time frame: 0 and 10 weeks

Change in Aerobic Performance

measured as a 5km time trial with a 250m hill segment (8% grade) at 1km and 4km on a treadmill

Time frame: 0 and 10 weeks

Change in Vertical Jump Height

measured using vertec

Data from ClinicalTrials.gov

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