The study aims to explore the effectiveness of psycho-behavioral intervention on depressive symptoms among older adults with chronic heart failure. Meanwhile, the effect on cardiac function and quality of life will also be explored.
Depression has been one of the emerging health concerns for older adults, especially for those with chronic heart failure (CHF). It was about 4-5 times more prevalent among patients with CHF than healthy population and independently associated with poor outcome of CHF. As suggested in the clinical management guideline of CHF, it is imperative to create integrative intervention for older adults with CHF, including timely detection and intervention, and ultimately improving the clinical outcome of CHF. However, the approach appropriate for depression intervention among Chinese older adults has yet been developed. This study aims to explore the effectiveness of psycho-behavioral intervention on depression associated with chronic heart failure in old age.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
236
The psycho-behavioral intervention included 12-week weekly guided psychological intervention (8 modules of behavioral intervention) and 24-week monthly maintenance psychological support.
Beijing Anzhen Hospital, Capital Medical University
Beijing, China
RECRUITINGBeijing Chaoyang Hospital, Capital Medical University
Beijing, China
RECRUITINGBeijing Chaoyang Third Hospital
Beijing, China
16 Item Quick Inventory of Depressive Symptomatology Self-Report Version
The primary outcome measure is the response rate of depression from baseline to week 12. The response rate was defined as a 50% or greater score reduction on 16 Item Quick Inventory of Depressive Symptomatology-Self-Report. The total score ranges from 0 to 27, with higher scores indicating more severe symptoms.
Time frame: between baseline and week 12
16 Item Quick Inventory of Depressive Symptomatology Self-Report Version
The severity of depressive symptoms was measured with the 16 Item Quick Inventory of Depressive Symptomatology Self-Report Version. The score ranges from 0 to 27, with higher scores indicating more severe symptoms.
Time frame: between baseline and week 1, 2, 4, 8, 24 and 36
17-Item Hamilton Rating Scale for Depression
The severity of depressive symptoms was measured with 17-Item Hamilton Rating Scale for Depression. The 17-item Hamilton Depression Rating Scale produces a total score ranging from 0 (not at all depressed) to 52 (severely depressed).
Time frame: between baseline and week 4, 8, 12, 24 and 36
Beck Depression Inventory II
The Beck Depression Inventory II assesses the severity of depression and produces a total score ranging from 0 to 63, with higher scores indicating more severe symptoms.
Time frame: between baseline and week 1, 2, 4, 8, 12, 24 and 36
Geriatric Depression Inventory-Self-Report
The Geriatric Depression Inventory-Self-Report assesses the severity of depression and produces a total score ranging from 0 to 12, with higher scores indicating more severe symptoms.
Time frame: between baseline and week 4, 8, 12, 24 and 36
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Beijing Fengtai Tieying Hospital
Beijing, China
RECRUITINGBeijing Tiancun Community Health Center
Beijing, China
RECRUITINGPeking University Third Hospital
Beijing, China
RECRUITINGamino-terminal fragment of pro-B-type natriuretic peptide (NT-ProBNP)
change of NT-ProBNP level
Time frame: between baseline and week 12, and between baseline and week 36
cardiac function
change of ejection fraction as measured with ultrasound cardiogram
Time frame: between baseline and week 12, and between baseline and week 36
Minnesota living with heart failure questionnaire
The health-related quality of life was measured by Minnesota Living with Heart Failure Questionnaire.The total score ranges from 0 to 105, with higher scores from best to worst health-related quality of life.
Time frame: between baseline and week 4, 8, 12, 24 and 36