The investigators will retrospectively analyze and compare data of 2 groups of overweight and obese patients: subjects who followed a diet based on Resting Energy Expenditure (REE) measured by indirect calorimetry and subjects who followed a diet based on REE estimated by the Harris-Benedict equation. Propensity score adjustment will be used to adjust for known differences between the 2 groups
Study Type
OBSERVATIONAL
Enrollment
355
Indirect calorimetry will be performed by using an open-circuit calorimeter (Sensor Medics, Italy). Indirect calorimetry is the reference method for energy expenditure determination. A canopy hood covered the patient's head and expired air is extracted by a pump to be analyzed by metabolic cart sensors; flow rate is directly measured with a digital turbine flowmeter. After an overnight fast, patients will asked to lay supine in complete physical rest, not sleeping or talking for approximately 20-25 minutes, at a room temperature ranged between 22 and 24°C. The mean REE for each participant considers the last 15-20 minutes of measurements corresponding to steady state. Software of calorimeter will be set for minute-by-minute reading report of VO2 (Oxygen flow) and VCO2 (Carbon dioxide flow) measurement. Parameters obtained by Indirect Calorimetry will be the Resting Energy Expenditure and the Respiratory Quotient (RQ)
San Donato Hospital
San Donato Milanese, MI, Italy
Weight in Indirect Calorimetry group and in NO Indirect Calorimetry group
To compare body weight variation (kg) in two groups of overweight or obese patients: subjects who followed a diet formulated on REE measured by IC (IC group) and subjects who followed a diet based on REE predicted by the Harris-Benedict formula (NO-IC group)
Time frame: 18 months
BMI in Indirect Calorimetry group and in NO Indirect Calorimetry
To compare BMI variation (kg/m\^2) in two groups of overweight or obese patients: subjects who followed a diet formulated on REE measured by IC (IC group) and subjects who followed a diet based on REE predicted by the Harris-Benedict formula (NO-IC group)
Time frame: 18 months
Weight in male/female in Indirect Calorimetry group and in NO indirect Calorimetry group
To identify gender differences in weight variation (kg) between IC and NO-IC groups
Time frame: 18 months
BMI in male/female in Indirect Calorimetry group and in NO indirect
To identify gender differences in BMI variation (kg/m\^2) between IC and NO-IC groups
Time frame: 18 months
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