This study compares the difference in proinflammatory markers Interleukin 6 (IL-6), Tumor necrosis factor alpha (TNFα) and cortisol in patients undergoing cardiovascular surgery to asses if there is a benefit of using intravenous total anesthesia (TIVA) over inhaled anesthesia for this procedures.
IL-6, TNFα and cortisol will be measure at the beginning of the cardiovascular surgery and 20 minutes after the cardiovascular bypass ends to calculate the difference between them and compare if there is any statistical difference between the proinflammatory markers with the two anesthesia techniques.
Study Type
OBSERVATIONAL
Enrollment
40
Propofol anesthesia Dose: 4-6mg/kg/h
Inhaled anesthesia with sevoflurane. Dose: 1-2.5 Minimum Alveolar Concentration(MAC)
Hospital de cardiología
Mexico City, Mexico City, Mexico
IL-6
IL-6 will be compared between the groups.
Time frame: The difference between IL-6 at the begging of surgery and 20 minutes after the end of the cardiopulmonary bypass
TNFα
TNFα will be compared between the groups
Time frame: The difference between TNFα at the begging of surgery and 20 minutes after the end of the cardiopulmonary bypass
Cortisol
Cortisol will be compared between the groups
Time frame: The difference between cortisol at the begging of surgery and 20 minutes after the end of the cardiopulmonary bypass
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