Salivary Glycated Albumin

University of Maryland, Baltimore

Overview

(1) to determine whether the ratio of glycated albumin and total albumin in saliva is equivalent to blood and (2) to investigate whether the non-invasive SmartAlbu portable salivary sensor is as accurate as standard tests that measure glycosylated hemoglobin (HbA1c).

Study Type

INTERVENTIONAL

Allocation

Purpose

OTHER

Masking

NONE

Conditions

Diabetes Mellitus

Interventions

SmartAlbuDEVICE

Plan: 1. Consent an individual 2. Measure and record temperature, blood pressure, heart rate, height and weight 3. Obtain two samples of saliva for the SmartAlbu portable salivary sensor 4. Take a venous blood sample for HbA1c and 5. Glycated albumin 6. Obtain blood sample from a finger stick for point of care HbA1c device

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 123 individuals with type 1 or type 2 diabetes * 53 non diabetic controls * Age: 18 to 80 * Body mass index \>18.5kg / m2 Exclusion Criteria: * Acute illness (within 7 days) - respiratory infection, fever above 38 °C, sinusitis infection, severe allergies. * Individuals with known sickle cell, pregnancy, hemoglobinopathies, renal failure * Subjects unable to give voluntary informed consent

Locations (1)

University of Maryland

Baltimore, Maryland, United States

Outcomes

Primary Outcomes

Salivary glycated albumin vs. blood glycated albumin

Whether the ratio of glycated albumin and total albumin in saliva is equivalent to blood.

Time frame: 30 min

Salivary glycated albumin vs. glycosylated hemoglobin (HbA1c)

To investigate whether the non-invasive SmartAlbu portable salivary sensor is as accurate as standard tests that measure HbA1c.

Time frame: 30 min

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.