Unbound Bilirubin Levels in Healthy Term and Late Preterm Infants

Rutgers University180 enrolled

Overview

Specific Aim 1: To determine total serum bilirubin (TSB) and unbound bilirubin (Bf) levels in term and late preterm infants during the first week of life. Specific Aim 2: Measure Bf levels in breast fed and formula fed infants and examine their relationship to unbound fatty acid (FFAu) levels. Specific Aim 3: To demonstrate that phototherapy results in different changes in TSB and Bf.

Study Type

OBSERVATIONAL

Enrollment

180

Conditions

Neonatal Jaundice

Interventions

Assessment of unbound bilirubin levelsOTHER

Collection of residual blood for measurement of unbound bilirubin

Eligibility

Sex: ALLMin age: 6 HoursMax age: 7 Days

Medical Language ↔ Plain English

Inclusion Criteria: * Term and late-preterm infants admitted to the regular care nursery of Robert Wood Johnson University Hospital will be eligible for the study Exclusion Criteria: * Infants suffering from genetic, chromosomal or surgical conditions will be excluded.

Locations (1)

Robert Wood Johnson University Hospital

New Brunswick, New Jersey, United States

RECRUITING

Outcomes

Primary Outcomes

Unbound bilirubin levels in term and late preterm infants

Time frame: Two years

Unbound bilirubin levels in breast-fed versus formula-fed term and late preterm infants

Time frame: Two years

Effect of phototherapy on unbound bilirubin levels

Time frame: Two years

Data from ClinicalTrials.gov

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