Clinical Evaluation of the VIPUN Balloon Catheter 0.1

Inclusion Criteria: * Signed Informed Consent * Aged between and including 18 and 65 years * BMI between and including 18 and 25 * Understand and able to read Dutch * In good health on the basis of medical history * Able to return home without driving a vehicle on visit days 1-4 * Will not operate machines on the same day of treatment (visits 1-4) * Females subjects of childbearing potential are willing to use adequate contraception * Refrains from herbal, vitamin and other dietary supplements on the day of the visits Exclusion Criteria: Exclusion criteria related to possible influence on end-points: * Dyspeptic symptoms (assessed with PAGI-SYM questionnaire) * Using any medication that might affect gastric function or visceral sensitivity * Known / suspected current use of illicit drugs * Known psychiatric or neurological illness * Any gastrointestinal surgery that could influence normal gastric function in the opinion of the investigator Exclusion criteria related to positioning of the catheter: * History of heart or vascular diseases like irregular heartbeats, angina or heart attack * Nasopharyngeal, upper GI or esophageal surgery in the last 30 days * Suspected basal skull fracture or severe maxillofacial trauma * History of thermal or chemical injury to upper respiratory tract or esophagus * Current esophageal or nasopharyngeal obstruction * Known coagulopathy * Known esophageal varices Exclusion criteria related to codeine administration: * History of opioid dependency * Known severely decreased kidney or liver function * Pregnant or breastfeeding women (pregnancy test will be performed on females with childbearing potential) * Known severe lung disease (e.g. asthma or emphysema) * Have known side-effects/allergic reactions when taking codeine/morphine * Known diabetic, fructose intolerance or malabsorption of glucose or galactose or sucrose-isomalase insufficiency. Exclusion criteria related to Sirupus simplex administration: • Known diabetic (saccharose), intolerance to or malabsorption of propylene glycol and methyl- and propylparahydroxybenzoate Exclusion criteria related to nutrients (Fortimel): • Have a known allergy or intolerance to cow milk, soy, saccharose or any other ingredient of Fortimel Energy