The study aims to explore whether prophylactic dietary supplementation with prebiotic inulin-type fructans is able to influence the intestinal microbiota and the frequency of infectious disease episodes in kindergarten children during a winter period.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
258
Frequency of infectious disease episodes
Time frame: 24 weeks period
microbiota composition
fecal microbiota composition (qPCR, illumina)
Time frame: 24 weeks period
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