Induction of Ovulation Using Clomiphene Citrate and N-acetyl Cysteine Versus Letrozole

Assiut University100 enrolled

Overview

Infertility is defined as a couple's inability to become pregnant after one year of unprotected intercourse in women 35 years old and younger, and for six months in women over age 35 years. In any given year, about 15 percent of couples in North America and Europe who are trying to conceive are infertile

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

100

Conditions

Infertility

Interventions

LetrozoleDRUG

oral tablets 5 mg

Clomiphene Citrate plus N acetyl cystineDRUG

Clomiphene Citrate 100 mg oral tablets+ N acetyl cystiene 600 mg

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All primary and secondary. Infertility due to anovulation Exclusion Criteria: * Male factor infertility, tubal factor. * Endocrineopathy * Hypothyrodism * Morbid obesity * Under weight * Patient with previous surgery including drilling of ovary, Clomiphene Citrate resistant to ovulation.

Outcomes

Primary Outcomes

rate of ovulation

ultrasound evaluation

Time frame: 3 months

Data from ClinicalTrials.gov

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