Skin Sympathetic Nerve Activity and Sympathetic Tone

N/AEnrolling By InvitationNCT03243448

Kaohsiung Medical University Chung-Ho Memorial Hospital1,000 enrolled

Overview

There are many sympathetic hyperactivity diseases in the investigators' clinical practice. However, the conventional method to measure the sympathetic nerve activity had many limitations such as clinical application, data interpretation and even therapeutic manipulation. Therefore the investigators would like to develop a non-invasive method to record the sympathetic nerve activity in the investigators' study that can help gathering the sympathetic nerve activity easily in the investigators' daily clinical situation. By the determination of sympathetic nerve activity status, the health caregiver can understand the disease more.

Study Type

OBSERVATIONAL

Enrollment

1,000

Conditions

Nerve; Disorder, Sympathetic Healthy

Eligibility

Sex: ALLMin age: 20 YearsMax age: 85 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Sympathetic hyperactivity diseases included: hypertension, heart failure atherosclerotic diseases, arrhythmias, cardiomyopathy, pulmonary hypertension, chronic obstructive pulmonary disease, sleep apnea, pulmonary embolism, hepatitis, liver cirrhosis, hepatopulmonary syndrome, hepatorenal syndrome, renal failure, nephritis, irritable bowel syndrome. * Healthy Volunteers Exclusion Criteria: * Pregnant

Outcomes

Primary Outcomes

Secondary Outcomes

ventricular arrhythmia

The electrocardiogram recording from the telemetry.

Time frame: 24 to 72 hours

Mortality

The mortality will be accessed by the chart review and telephone access

Time frame: 1 to 12 months

Morbidity

The morbidity will be accessed by the chart review and telephone access

Time frame: 1 to 12 months