An endoscopic third ventriculostomy is considered to be successful in idiopathic normal pressure hydrocephalus (iNPH) in some literature reports, but there is a lack of high quality data. The aim of the present study is to compare the treatment options of iNPH (Endoscopic third ventriculostomy versus ventriculo-peritoneal shunt) in a randomized, controlled, multicenter study.
The traditional treatment for communicating hydrocephalus is a ventriculo-peritoneal shunt insertion and the endoscopic third ventriculostomy (ETV) is reserved for patients with obstructive hydrocephalus. However, in the last decade several reports highlighted an success of an ETV in communicating hydrocephalus as well. Thus, the aim of the present study is to compare ventriculo-peritoneal shunting against ETV in patients with an idiopathic normal pressure hydrocephalus, an subset of communicating hydrocephalus, in a randomized, controlled multicenter study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
100
patients receive an endoscopic third ventriculotomy as surgical procedure
patients receive an ventriculo-peritoneal shunt as surgical procedure
University Medicine Göttingen
Göttingen, Germany
NOT_YET_RECRUITINGUniversity Medicine Greifswald
Greifswald, Germany
RECRUITINGKlinikum Neubrandenburg
Neubrandenburg, Germany
RECRUITINGKiefer Index
Improvment of at least 2 points
Time frame: 1 year
Recovery Index
Improvment of at least 2 points
Time frame: 1 year
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