This study will evaluate if the timing of oxytocin administration in cesarean deliveries will affect the amount of maternal blood loss. Half of participants will receive oxytocin after delivery of the fetal anterior shoulder and the other half will receive oxytocin after delivery of the placenta. We hypothesize that administering oxytocin after delivery of the shoulder, will result in less overall maternal blood loss.
Oxytocin is a routinely administered medication for both vaginal and cesarean deliveries in the third stage of labor, as part of standard of care in the United States. This medication helps to reduce overall blood loss, by functioning as a uterotonic. Currently evidence is lacking to direct timing of oxytocin administration in cesarean deliveries. This study will evaluate both estimated and quantitative blood loss for both groups of patients. It will also compare the change from pre-operative to post-operative hemoglobin levels.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
68
Loyola University Medical Center
Maywood, Illinois, United States
Total blood loss
Both the estimated blood loss and quantitative blood loss will be determined
Time frame: At the completion of the surgery when patient is transferred to recovery from the operating room
Incidence of postpartum hemorrhage
The number of women who lose 1,000 milliliters or more blood from cesarean delivery
Time frame: At the completion of the surgery when patient is transferred to recovery from the operating room
Need for transfusion
The number of women who require a blood transfusion due to surgical blood loss
Time frame: In the immediate 24 hours post surgery
Change in pre-operative to post-operative hemoglobin levels
Hemoglobin levels
Time frame: Baseline and Post operative day number 1
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