A Prospective Study: the Value of Using iFlow and PBV in the Endovascular Treatment of Infrapopliteal Arterial Occlusive Diseases

Inclusion Criteria: 1. Patients are diagnosed as lower limb atherosclerosis occlusion from June 2016 to June 2018 in our centre; 2. All participating patients provided written informed consent and willing to participate; 3. aged 40 years and more; 4. the class of lower ischemia is upon 4; 5. below-the-knee arteries stenosis or occlusion is indicated by duplex or computed tomographic angiography; 6. there is no heavy stenosis in superficial femoral artery (stenosis\<30%), or short length lesion(length≤5cm, stenosis≥30%); 7. infection or ulceration don't happen in the area of surgery; 8. below the inguinal ligament arteries don't have the history of bypass or interventional surgery. Exclusion Criteria: 1. disagree and refuse to the free therapy; 2. lesion length of superior artery is more than 5cm; 3. history of heart dysfunction: congestive heart failure,, myocardial infarction, severe arrhythmia; 4. With severe metabolic disease, renal impairment(serum creatinine\>1.4mg/dL, glomerular filtration rate\<60) affect the excretion of contrast agents; 5. have the diseases or agents which will reduce the viable of data; 6. allergy to iodinated contrast medium.