The aim of this study is to investigate whether an individualized determination of energy requirements using indirect calorimetry instead of a formula-based approach leads to an optimized nutritional support and as a consequence to an optimized nutritional status of the critically ill, mechanically ventilated patients measured by the phase angle.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
40
Energy need is being determined using indirect Calorimetry
University of Hohenheim
Stuttgart, Germany
Phase angle (PhA)
The primary endpoint is the change of the phase angle during the stay in the intensive care unit (ICU). A mean difference of 5% is considered as relevant.
Time frame: PhA was measured between one and 90 days (during ICU stay)
Nitrogen Balance
Difference between intervention and control group between hospital admission and discharge.
Time frame: Nitrogen Balance was measured between one and 90 days (during ICU stay)
Extracellular to body cell mass ratio (ECM/BCM - Ratio)
Difference between intervention and control group between hospital admission and discharge.
Time frame: ECM/BCM-Ratio was measured between one and 90 days (during ICU stay)
Length of hospital stay in days
Difference between intervention and control group between hospital admission and discharge.
Time frame: Length of hospital stay was measured between one and 180 days
Length of stay in intensive care unit (ICU) in days
Difference between intervention and control group between hospital admission and discharge.
Time frame: Length of ICU stay was measured between one and 90 days
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