PD-1(Programmed Death-1) Antibody +GP as First Line Treatment for Triple Negative Breast Cancer(TNBC) Patients

Inclusion Criteria: * Histologically confirmed relapsed or metastatic triple negative breast cancer * Subjects must have normal organ and marrow function as defined below: * White blood cell ≥ 3,000/μL, Absolute neutrophil count ≥ 1,500/μL, Hemoglobin ≥ 9.0 g/dl, Platelet count ≥ 100,000/μL * Total bilirubin ≤1.25 X institutional upper limit of normal , aspartate aminotransferase(AST) ≤ 2.5 X institutional upper limit of normal, alanine transaminase(ALT) ≤ 2.5 X institutional upper limit of normal (For patients with liver metastasis, Total bilirubin ≤1.5 X institutional upper limit of normal , AST ≤5 X institutional upper limit of normal, ALT ≤5 X institutional upper limit of normal) * Serum creatinine within normal institutional limits * thyroid-stimulating hormone ,FT3(free triiodothyronine),FT4(Free thyroid hormone) within 0.9 X institutional lower limit of normal to 1.1 X institutional upper limit of normal (Except for patients who had thyroid ectomy) * Basically normal EKG and left ventricular ejection fraction(LVEF)\>50% * Life expectancy of 6 months or more * Performance Status 0-1 * Subjects must have at least one measurable disease per RECIST v1.1 * Weight more than 45 Kilogram * Subjects must have not received chemotherapy in metastatic setting, subjects relapsed 6 months after the completion of adjuvant therapy are eligible * Subjects must be willing to supply fresh or archive tumor tissue for research purposes * Subjects must have stopped receiving any anti-cancer treatment (including chemotherapy, curative radiotherapy, and surgery or targeting therapy) for at least 4 weeks. * Subjects must have stopped receiving systemic immunosuppressive agents for at least 2 weeks. * Subjects must have the ability to understand and the willingness to sign a written informed consent document Exclusion Criteria: * Subjects with radiographically stable treated brain metastases are eligible but must not have been on steroid therapy for at least 4 weeks * History of allergic reactions attributed to compounds of similar chemical or biologic composition to Gemcitabine, cisplatin or JS001 * Patients who have adjuvant chemotherapy and relapsed within 6 months. * Pregnant or breastfeeding women are excluded from this study * Patients with HIV infection, patients with positive HbsAg or HCV(hepatitis C virus)-RNA * Patients with chronic autoimmune disease * Patients with prior therapy with antibodies that modulate T-cell function (e.g., anti-PD-1, anti-PD-L1, anti-CTLA-4(Cytotoxic T-lymphocyte-associated protein 4)) * Patients with evidence of active, non-infectious pneumonia * Patients with a history of tuberculosis * Patients active infection requiring intravenous systemic therapy * Severe cardiovascular disease * Severe gastrointestinal dysfunction (bleeding, infection, obstruction or ≥ grade 1 diarrhea) * Patients with severe coagulation dysfunction or bleeding tendency, patients who are receiving thrombolysis or anticoagulation therapy * Subjects with uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, severe hyper blood pressure, severe diabetes or severe thyroid disease that would limit compliance with study requirements * Patients with known psychiatric disorders that would interfere with cooperation with requirements of the trial * Patients who have received a vaccine within 4 weeks prior to the first dose of JS001 * Patients with a known additional malignancy that is progressing or requires active treatment (within the last 5 years). Exceptions: basal cell carcinoma of the skin, squamous cell carcinoma of the skin or in situ cancers that has undergone potentially curative therapy