Effectiveness of Lower Maintenance Dose of Ticagrelor Early After Myocardial Infarction (ELECTRA) Pilot Study

Inclusion Criteria: * provision of informed consent prior to any study specific procedures * diagnosis of acute ST-segment elevation myocardial infarction or acute non-ST-segment elevation myocardial infarction according to the Third Universal Definition of Myocardial Infarction * index event treatment with percutaneous coronary intervention * male or non-pregnant female, aged 18-80 years old Exclusion Criteria: * contraindications for ticagrelor * further coronary revascularization planned during the first 45 days after myocardial infarction * indications for chronic treatment with oral anticoagulant or low-molecular-weight heparin * active bleeding * history of intracranial hemorrhage * recent gastrointestinal bleeding (within 30 days) * history of coagulation disorders * history of moderate or severe hepatic impairment * history of major surgery or severe trauma (within 3 months) * active neoplastic disease * patient requiring dialysis * chronic inflammatory disease * current therapy with strong CYP3A inhibitors or strong CYP3A inducers