Survey of QRS Frequency at Various Left Ventricular Pacing Sites for Cardiac Resynchronization

The Cleveland Clinic14 enrolled

Overview

LV pacing at various sites with recording of ECG and subsequent signal analysis at different sites.

During routine cardiac resynchronization pacemaker or implantable defibrillator (ICD) implantation (including de-novo and upgrade from standard device, additional pacing within 3 different coronary veins will be performed in combination with a previously implanted right ventricular pacing or ICD lead. The resulting electrocardiogram signal will be analyzed afterwards. A time-frequency analysis (TFA) of several ECG leads at each paced site will be performed and compared. The results of the TFA analysis will not be used to select pacing lead location in this study. The patient will then receive the left ventricular pacing lead in the standard manner.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Cardiomyopathies Congestive Heart Failure

Interventions

Biotronik Vision GuidewireDEVICE

The apical, mid ventricular and basal sites within the anterior,posterior and lateral coronary sinus branch veins will be paced.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Standard implantation for cardiac resynchronization ICD or PM implantation * Cardiomyopathy with LVEF \<35% * QRS duration greater than 120 msec Exclusion Criteria: \- Age less than 18 years

Locations (1)

Cleveland Clinic

Cleveland, Ohio, United States

Outcomes

Primary Outcomes

QRS Frequency at Each Paced Location

Time frequency analysis performed at each location

Time frame: Baseline

Data from ClinicalTrials.gov

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