The purpose of this study is to evaluate BMS-986165 tablet formulation versus BMS-986165 capsule formulation. This study will also evaluate the effect of a high-fat/ high-calorie meal and increased gastric pH on the BMS-986165 tablet formulation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
49
Oral capsule
Oral tablet
PRA Health Sciences
Lenexa, Kansas, United States
Maximum observed plasma concentration (Cmax) derived from plasma concentration versus time
Time frame: 5 days
AUC from time zero extrapolated to infinity [AUC(INF)] derived from plasma concentration versus time
Time frame: 5 days
Area under the plasma concentration-time curve (AUC) from time zero to time of last quantifiable concentration [AUC(0-T)] derived from plasma concentration versus time
Time frame: 5 days
Time of maximum observed plasma concentration (Tmax) derived from plasma concentration versus time
Time frame: 5 days
Adverse events measured by incidence
Time frame: 26 days
Serious adverse events measured by incidence
Time frame: Approximately 55 days
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