Hypertension is the major risk factor for cardiovascular and cerebrovascular diseases worldwide. The escalating prevalence of inadequate sleep now parallels that of hypertension. Observational and experimental evidence favoring a causal relation between insufficient sleep and hypertension are particularly compelling - sleeping 6 hours or less per night is associated with a 20-32% higher probability of incident hypertension. Since sleep curtailment is largely voluntary, sleep deficiency may be corrected and the detrimental health consequences potentially reversed. In this study the investigators aim to investigate the effects of 8 weeks of sleep enhancement/extension vs health education in prehypertensive and stage 1 hypertensive subjects who report habitual short sleep (≤6.5 hours/night).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
110
This regimen combines education and behavioral skills to enable prolonging sleep in chronically sleep deprived subjects so as to better meet participant's sleep needs. This intervention emphasizes plain language communication of cognitive behavioral therapy strategies for initiating and maintaining health behavior change, primarily through using brief action plans (time-limited, personally relevant, behavioral goal setting with confidence), and collaborative problem-solving. Coaching will be provided to modify daily routines and adhere to sleep hygiene practices to allow for extended time in bed.
This is a placebo/attention control condition. Participants will receive health education based on NIH information. Number, duration, and frequency of sessions will be identical to those administered to the intervention group.
Mayo Clinic in Rochester
Rochester, Minnesota, United States
change in 48-hour mean arterial pressure
changes in ambulatory measure of blood pressure
Time frame: 8 weeks
changes in 48-hour heart rate
changes in 24-hour heart rate
Time frame: 8 weeks
changes in baroreflex sensitivity
changes in baroreflex sensitivity
Time frame: 8 weeks
changes in endothelial function
changes in endothelial function
Time frame: 8 weeks
changes in renin
changes in renin
Time frame: 8 weeks
changes in angiotensin peptides
changes in angiotensin peptides
Time frame: 8 weeks
changes in aldosterone
changes in aldosterone
Time frame: 8 weeks
changes in insulin sensitivity
changes in insulin sensitivity
Time frame: 8 weeks
changes in cortisol
changes in cortisol
Time frame: 8 weeks
changes in body fat
changes in body fat
Time frame: 8 weeks
changes in catecholamines
changes in catecholamines
Time frame: 8 weeks
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