This study will investigate the effect of two dietary patterns on sleep outcomes and measures of reported appetite. Participants will be given two different diets on two separate stays.
Normal sleep consists of alternating periods of non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. The deeper stages of NREM sleep are also known as slow-wave sleep (SWS). Genetic and environmental factors, such as age, gender, race, socioeconomic status and others contribute to high inter-individual variability in sleep quality. Current evidence from epidemiologic, clinical and experimental studies support a strong relationship between insufficient sleep and increased risk for obesity. A reciprocal connection between sleep and energy metabolism may exist between diet and sleep. It is also well known that diet greatly influences body weight and metabolic health. Numerous disease risk factors are known to be associated with dietary patters consisting low fiber, high saturated fat, and added sugar, but the effects of diet on sleep quality remains unknown. A small group of studies have indicated an effect of diet on sleep quality (assessed objectively by polysomnography \[PSG\]) under controlled laboratory conditions. However, none have experimentally tested sleep and appetite outcomes under different dietary patterns matched for macronutrients. The overall objective of this study is to compare the effects of consumption of unhealthy meals with low fiber, high saturated fat, and high added sugar content i.e. simulated fast food diet \[SFF\] to healthy meals with high fiber, low saturated fat, and low added sugar content i.e. healthy diet. We hypothesize that a healthy diet (as recommended by the Dietary Guidelines Advisory Committee and the American Heart Association) compared to SFF diet will promote better sleep quality (as assessed by PSG) reflected by higher sleep efficiency, increased SWS and increased REM sleep and other improved sleep variables. We will also evaluate subjective appetite, mood and sleepiness as secondary outcomes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
5
Diets matched for calorie intake and macronutrient distribution but differing by overall diet quality will be provided in a random order, cross-over design study.
Univeristy of Chicago
Chicago, Illinois, United States
Sleep quality night 2
Night 2 PSG recordings
Time frame: Bedtime (11:00PM) to Wake time (7:30AM)
Subjective appetite area under the curve
A collection of all subjective ratings (upon waking, pre and post meals, and hourly)
Time frame: 7:30am-11:00PM
Subjective appetite daily average
A collection of all subjective ratings (upon waking, pre and post meals, and hourly)
Time frame: 7:30am-11:00PM
Mood area under the curve
A collection of all subjective ratings (upon waking, pre and post meals, and hourly)
Time frame: 7:30am-11:00PM
Mood daily average
A collection of all subjective ratings (upon waking, pre and post meals, and hourly)
Time frame: 7:30am-11:00PM
Subjective sleep quality area under the curve
A collection of all subjective ratings (upon waking, pre and post meals, and hourly)
Time frame: 7:30am-11:00PM
Subjective sleep quality daily average
A collection of all subjective ratings (upon waking, pre and post meals, and hourly)
Time frame: 7:30am-11:00PM
Sleep quality night 1
Night 2 PSG recordings
Time frame: 11:00PM to 7:30AM
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Sleep night 1
Measured with wrist actigraphy
Time frame: 11:00PM to 7:30AM
Sleep night 2
Measured with wrist actigraphy
Time frame: 11:00PM to 7:30AM
Sleep night 3
Measured with wrist actigraphy
Time frame: 11:00PM to 7:30AM