The aim of this study is to evaluate the efficacy of alpha lipoic acid on uterine scar healing after cesarean section by using saline contrast sonohysterography
This is a triple blind randomized placebo controlled prospective clinical trial that will be conducted in Ain Shams University Maternity Hospital. in which a consecutive series of participant attending emergency room 102 women undergoing cesarean section for the first time will be randomized into two groups. Group A (Study group): 51 women will receive alpha lipoic acid drug ( 600 mg twice daily) for 6 weeks after cesarean section and saline sonohysterography will be done after that. Group B (Control group): 51 women will receive a placebo drug twice daily for 6 weeks after cesarean section and saline sonohysterography will be done after that.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
102
Alpha lipoic acid has anti-inflammatory, antioxidant effects and plays a role in wound healing process.
placebo oral drug have the same shape of thiotacid tablet
Ain Shams University Maternity Hospital
Cairo, Abbassia, Egypt
presence of scar niche
triangular shaped anechoic area at the site of incision
Time frame: six weeks after CS
The healing ratio
the thickness of residual myometrium covering the defect divided by the sum of the thickness of residual myometrium cover the defect and the height of wedge shaped defect
Time frame: six weeks after CS
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