Effect of Combined Fatty Acid Supplementation and Eccentric Exercise Training on Exercise Performance

Loughborough University18 enrolled

Overview

The aim of the study is to determine whether fish oil (specifically omega-3 long chain polyunsaturated fatty acids \[EPA-DHA\]) supplementation can enhance eccentric resistance exercise performance when combined with a resistance exercise training study. The investigators aim to establish the potential mechanisms that might mediate performance changes at a cellular level.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Enrollment

Conditions

Exercise-induced Inflammation

Interventions

Fish OilDIETARY_SUPPLEMENT

Fish Oil Capsule

PlaceboDIETARY_SUPPLEMENT

Olive Oil capsule manufactured to mimic fish oil capsule

Eligibility

Sex: MALEMin age: 18 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Males * Healthy Exclusion Criteria: * Resistance exercise training within the past 6 months * Vitamin or fish oil supplementation over the past 6 months * Habitual use of anti-inflammatory drugs * History of heart disease * History of coagulation/bleeding disorder * History of metabolic disease * Serious allergy * Known to have blood-borne virus * Females (Due to differences in cell membrane incorporation of Omega-3 between the sexes and the testing schedule being unable to fit in with menstrual cycle, altering the blood markers that are being measured) * Currently no symptoms of general illness

Locations (1)

Loughborough University

Leicester, United Kingdom

Outcomes

Primary Outcomes

Strength

Quadriceps and Hamstring strength using an isokinetic dynamometer

Time frame: Change from baseline strength at 11 weeks

Leg power

Dynamic leg power assessed through jump height on force platform

Time frame: Change from baseline strength at 11 weeks

Data from ClinicalTrials.gov

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