Safety of Transarterial Chemoembolization (TACE) in the Setting of an Elevated Bilirubin

Inclusion Criteria: * hepatocellular carcinoma (HCC) * Direct or conjugated bilirubin \< 3 mg/dl * Total bilirubin \> 3 mg/dl * Willing and able to provide informed consent * \>18 years of age Exclusion Criteria: * Currently pregnant * Patients who are surgical or ablation candidates as determined by multidisciplinary hepatobiliary tumor conference. * Arterial anatomy which would preclude selective transarterial chemoembolization * Patients who have a INR or platelet count which are not correctable to \<1.8 and \>35,000 respectively * Patients with extrahepatic metastases * Patients with portal vein invasion