Renal functional reserve may be improved in patients with simple renal cysts after laparoscopic deroofing.
Simple renal cysts (SRC) are the most frequent type of cystic renal disease. The prevalence rate of SRCs is about 10% and increases with age. Hypertension and decreased renal functions have been reported to occur more commonly among these patients with SRC and there are no clear guidelines for managing asymptomatic SRCs.Renal functional reserve (RFR) describes the capacity of the intact nephron mass to increase glomerular filtration rate(GFR) from baseline in response to stimuli (e.g., protein load).The investigators hypothesized that RFR may be improved in some patients with simple renal cysts after laparoscopic deroofing despite identical resting glomerular filtration rate (rGFR).The aim of this study is to examine whether there is improvement of RFR in patients with simple renal cysts after laparoscopic deroofing.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
200
The classic treatment of patients with simple renal cysts is deroofing, which can be performed by open surgery or laparoscopy. Laparoscopic deroofing is an effective minimally invasive approach and has gained popularity.
intravenous supplementation with 100 g of amino acids 2 day before laparoscopic deroofing.
Xuanwu Hospital Capital Medical University
Beijing, Beijing Municipality, China
RECRUITINGChange in renal functional reserve after laparoscopic deroofing
1 month after surgery, repeated glomerular filtration rate measurements are to be performed to calculate change in renal functional reserve.
Time frame: 1 month after surgery.
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