Compare the use of nandrolone associated with corticosteroid for the treatment of cancer-induced malnutrition to treatment with corticosteroids alone in patients with tumors in the high gastro-intestinal tract, liver, pancreas and bile ducts in palliative treatment.
* Compare muscle mass values obtained before and after the use of anabolic steroids upon assessment by bioelectrical impedance analysis (BIA). * Compare the anabolic effect on quality of life (QLo) of the patient before and after the use of anabolic steroids. * Compare data from laboratory tests such as complete blood count, albumin, C reactive protein and transferrin with drug intervention.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
60
Drug administration
Drug administration
Hospital Erasto Gaertner
Curitiba, Paraná, Brazil
Compare the use of nandrolone associated with corticosteroid for the treatment of cancer-induced malnutrition to treatment with corticosteroids alone in cancer patients
Evaluate the BMI ( body mass index)- the weight in kilograms and the height in centimeters and BMI in Kg/ m2.
Time frame: After 30 days, the values will be compared to those obtained on the first consultant.
Compare the use of nandrolone associated with corticosteroid for the treatment of cancer-induced malnutrition to treatment with corticosteroids alone in cancer patients by bioimpedance analysis ( BIA)
Evaluate the BIA (biometrical impedance analysis)trough the reactance and resistance in ohms and the phase angle in degree.
Time frame: After 30 days, the values will be compared to those obtained on the first consultant.
ompare the use of nandrolone associated with corticosteroid for the treatment of cancer-induced malnutrition to treatment with corticosteroids alone in cancer patients trough quality of life assessment
Evaluate quality of life by European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnare Core 30 ( QLQ-C30), version 3.0 . The values are expressed as a percentage
Time frame: After 30 days, the values will be compared to those obtained on the first consultant.
Compare data from laboratory tests: complete blood count, albumin, C reactive protein and transferrin with drug intervention.
The complete blood count will be expressed in millions by cubic milimiter( millions/mm3) , albumin in grams per deciliter (g/dL), C reactive protein in milligrams per deciliter (mg/dL), transferrin in milligrams per deciliter (mg/dL)
Time frame: After 30 days, the laboratory test will be collect again and the values will be compared to those obtained on the first consultant.
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