Correlation Between Respiratory Variability of R-R Intervals and Systolic Pressure Variability

Rambam Health Care Campus40 enrolled

Overview

This prospective study is designed to assess and quantify the correlation between respiratory changes in R-R interval and the respiratory changed in invasive systolic blood pressure in ventilated patients during changes in posture and peak end expiratory pressure (PEEP) and following a fluid bolus

Study Type

OBSERVATIONAL

Enrollment

Conditions

Heart Rate Determination

Interventions

posture changesOTHER

Following induction of general anesthesia and initiation of positive pressure ventilation, patients will be tilted 15 degrees head up for 5 minutes with positive end expiratory pressure of 8 cm H2O, and then 15 degrees head down for 5 minutes with positive end expiratory pressure of 3 cm H2O

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-80 * Scheduled for surgery under general anesthesia requiring invasive blood pressure monitoring Exclusion Criteria: * Heart Rate other than sinus * Cardiac Pacemaker Status * Transplanted Heart

Outcomes

Primary Outcomes

Statistical Correlation between respiratory variability of R-R interval and systolic blood pressure

Time frame: From immediately after induction of general anesthesia and mechanical ventilation to 20 minutes later

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.