INR Comparison Testing in Cardiac Surgery

University of Miami50 enrolled

Overview

The investigator is testing blood samples to compare the results of two different techniques. Since blood loss and the need for blood transfusions continue to be major problems after heart surgery and other types of surgery, the blood clotting levels are constantly checked during heart surgery as part of clinical care.The purpose of this study is to compare the INR levels in blood before and after the heart bypass during surgery.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Coagulation Disorder

Interventions

International Normal Ratio (INR)DIAGNOSTIC_TEST

Blood test for INR using laboratory and point of care methods

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients greater than or equal to 18 years of age. * Patients undergoing elective surgery. * Patients undergoing cardiac surgery. * Patients to undergo general anesthesia with endotracheal intubation. * Patients with well-controlled health disorders. Exclusion Criteria: * Patients currently on Coumadin or other anticoagulants; including, direct thrombin inhibitors and direct Xa inhibitors. * Patients who are under 18 years of age or pregnant. * Patients undergoing emergency surgery. * Patients with known coagulation disorders. * Patients who are unable to provide informed consent in the form of a signature

Locations (1)

University of Miami Hospital

Miami, Florida, United States

Outcomes

Primary Outcomes

Change in correlation between laboratory and point of care INR

Pearson's Coefficient

Time frame: Baseline, Within ten minutes of completion of bypass

Secondary Outcomes

Change in agreement between laboratory and point of care INR

Bland-Altman plots

Time frame: Baseline, Within ten minutes of completion of bypass

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.