Lamina Cribrosa Depth Change With Change in Eye Pressure

Johns Hopkins University309 enrolled

Overview

This is a study of the compliance of the lamina cribrosa with change in eye pressure.

Glaucoma patients and control subjects will have their internal eye structure (lamina cribrosa) imaged by optical coherence tomography (OCT) standard images at two different eye pressures. In some participants, the eye pressure will be changed by one of two interventions, wearing goggles or having laser suturelysis

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

309

Conditions

Glaucoma, Open-Angle

Interventions

wearing swimming goggles or having laser suturelysisOTHER

Two images will be compared in each subject at two different eye pressures with the higher pressure having been produced by the interventions

Eligibility

Sex: ALLMin age: 21 YearsMax age: 100 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * persons who consent to drink water and be imaged Exclusion Criteria: * non-consenting persons * those who cannot be imaged

Locations (1)

Johns Hopkins University

Baltimore, Maryland, United States

Outcomes

Primary Outcomes

Change in anterior lamina cribrosa depth

OCT position of lamina measured at 2 eye pressures. Data will be calculated as change in parameters of interest per mm Hg change in eye pressure

Time frame: Up to 2 months

Data from ClinicalTrials.gov

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