New Orleans Pulmonary Hypertension Biobank

Louisiana State University Health Sciences Center in New Orleans450 enrolled

Overview

Pulmonary hypertension (PH) is a serious condition characterized by a mean pulmonary artery pressure \>=25mmHg on right heart catheterization (RHC). Despite advances in PH care, outcomes are still sub-optimal and further research is required into the pathobiology of the disease and development of biomarkers that can guide clinical care. The investigators are establishing a biobank to collect samples (blood, urine, stool) from patients with pulmonary hypertension, patients at high risk for pulmonary hypertension, healthy controls, and patients undergoing right heart catheterization. Specimens will be stored for future investigations.

Study Type

OBSERVATIONAL

Enrollment

450

Conditions

Pulmonary Hypertension Systemic Sclerosis Mixed Connective Tissue Disease Heart Failure With Normal Ejection Fraction Healthy

Interventions

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of pulmonary hypertension and followed at the Comprehensive Pulmonary Hypertension Center OR * Diagnosis of systemic sclerosis and followed at the Comprehensive Pulmonary Hypertension Center OR * Diagnosis of mixed connective tissue disease and followed at the Comprehensive Pulmonary Hypertension Center OR * Undergoing outpatient right heart catheterization Exclusion Criteria: * Age\<18 * Pregnant * Unable to understand English * Currently incarcerated * Unwilling or unable to sign informed consent

Outcomes

Primary Outcomes

Collection of biospecimens

Biospecimen collection only

Time frame: 10 years