Cardiovascular Biomarkers and Lung Edema in Severe Burns Patients

Inclusion Criteria: * Intubated mechanically-ventilated patients within the first 24 hours of admission * And/or patients with total body surface area (TBSA) burn-injured \>20 % * And/or patients with at least 10% full-thickness burns * And/or receiving vasopressors within the first 24 hours of admission * And monitored by a PiCCO system (PiCCO-2 Pulsion Medical Systems AG, Munich, Germany) Exclusion Criteria: * Admission delay to ICU \> 24 hours post burn * Age less than 18 years * Pregnancy * Chronic renal impairment with a baseline eGFR \< 15 ml/min * Patients with chemical or electrical burns * Coexisting non-burn trauma * Patients moribund on admission or dead within 72 h from admission * Patients with do-not-resuscitate orders