The objective of this observatory is to provide a national database of infective endocarditis, informed by all volunteer centers, using a standardized case report forms. Such an observatory will describe the clinical profile, microbiological, therapeutic and evolving of infective endocarditis (IE); analyze the risk factors for the disease and its prognosis factors of evolution; describe management practices; evaluate and compare in the real drug treatment strategies (including antibiotics) and surgical.
All the clinical, biological, microbiological and laboratory describing the history of patients and their evolution during hospitalization for infective endocarditis will be obtained from physicians supporting patients and recorded in an electronic case report form. Will include collected clinical characteristics (site, pre-existing heart disease underlying symptoms, complications), biological characteristics (dosage on admission and diagnosis), microbiological characteristics (identifying the genus and species of the microorganism responsible, sensitivity to antibiotics susceptibility testing and evaluated by determination of minimal inhibiting concentration (MIC), exhaustive search of the rare forms of endocarditis uncultivated microorganisms), an analysis of the gateways based on the causative organism; echocardiographic characteristics (number and size of vegetations, valvular damage, scalable: surgery, lethality) and therapeutic characteristics (antibiotic treatment, surgical).
Study Type
OBSERVATIONAL
Enrollment
5,000
CHRU
Vandœuvre-lès-Nancy, France
RECRUITINGhistory of heart disease
status of heart valves, pre-existing heart conditions
Time frame: inclusion
risk factors, medical history
associated diseases
Time frame: inclusion
origin of infection
high risk procedures
Time frame: period of 3 months before infective endocarditis
weight
kg
Time frame: inclusion
height
cm
Time frame: inclusion
clinical symptoms
cardiac, peripheral and neurological symptoms
Time frame: inclusion
biological outcomes
blood count
Time frame: inclusion
microbiological outcomes
identification of infecting organisms
Time frame: inclusion
diagnostic imaging
description of tyhe imaging tests performed
Time frame: inclusion
antibiotic therapy
antibiotic treatment: type and duration
Time frame: from inclusion to recovery
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
surgical procedures
description of surgical procedures
Time frame: from inclusion to recovery
biologic collection (optional)
plasma and serum collection
Time frame: inclusion