Comparison of Rainbow INVSENSOR00001 and Control SpHb Disposable Sensor Performance During Hemodilution

Inclusion Criteria: * Competent adults between the ages of 18 and 50 years of age * Must weigh a minimum of 110 lbs and no more than 250 lbs unless subject is over 6 feet tall * BMI ≤ 35 unless the physician determines that a higher BMI is not due to morbid obesity, to safeguard subject safety during hemodilution * Must have a hemoglobin value ≥ 11 g/dL at time of screening, to safeguard subject safety during hemodilution * Baseline heart rate between 45 bpm and 85 bpm * CO value less than 2.0% FCOHb * Physical status of ASA I or II (American Society of Anesthesiology Class I; Healthy subjects without any systemic disease at all. American Society of Anesthesiology Class II; subjects with mild systemic disease) The ASA definition strictly applies to the systemic disease portion of the classification * Systolic BP less than or equal to 140 mmHg and Diastolic BP less than or equal to 90 mmHg * Able to read and communicate in English Exclusion Criteria: * Pregnancy or positive hCG test * Smokers (including e-cigarette users) * Subject has known drug or alcohol abuse. Subjects who uses recreational drugs * Subject has experienced a concussion or head injury with loss of consciousness within the last year * Any chronic bleeding disorders (i.e. hemophilia) * Any history of a stroke, myocardial infarction, or seizures * Any cancer or history of cancer (not including skin cancer) * Chronic neurological diseases (i.e. multiple sclerosis, Huntington's Disease) * Any cardiac dysrhythmias (i.e. atrial fibrillation)(without physicians clearance) * Subject has known neurological and/or psychiatric disorder (i.e. schizophrenia, bipolar disorder) that interferes with the subject's level of consciousness * Subject has Wolff-Parkinson-White Syndrome or Stokes-Adams Syndrome * Subjects who have/are currently taking anticoagulant medication * Subjects who have taken opioid pain medication within 24 hours of start of study * Subjects who do not understand the study and the risks * Subjects having either signs or history of peripheral ischemia * Subjects who have had invasive surgery within the past year- including but not limited to major dental surgery, gallbladder, heart, appendix, major fracture repairs (involving plates/ screws), jaw surgery, urinary tract surgery, plastic surgery, major ENT surgery, joint replacement or gynecological surgeries, heart surgery or thoracic surgery * Subjects that have symptoms of congestion, head colds, flu, or other illnesses * Subjects with claustrophobia, or generalized anxiety disorder * Subjects who have been in severe car accident(s) or a similar type of accident(s) requiring hospitalization within the last 12 months * Subjects with chronic unresolved asthma, lung disease and respiratory disease * Subjects with allergies to lidocaine, latex, adhesives, or plastic * Subjects with heart conditions, insulin-dependent diabetes or uncontrolled hypertension * Subjects who have given vaginal delivery, had a pregnancy terminated, a miscarriage with hospitalization or had a c-section within the last 6 months * Subjects who intend on participating in any heavy lifting, repetitive movement of their wrist (including riding a motorcycle) or exercise (working out, riding a bike, riding a skate board etc.), or any activity that will put additional stress on the wrist within 24 hours following a study involving an arterial blood draw and/or arterial line placement * Subject has any medical condition which in the judgment of the investigator and/or medical staff, renders them ineligible for participation in this study (Discretion of investigator)