Use of Injectable-platelet-rich-fibrin (I-PRF) to Thicken Gingival Phenotype

Bezmialem Vakif University29 enrolled

Overview

The main objective of this study is to investigate whether the for individuals with thin gingival thickness who are susceptible to gingival recession, the investigators will use i-PRF with microneedle to increase gingival thickness without the need for surgical procedures

Due to the thin gingival phenotype, gingival recession is a problem. The investigators aimed to increase the gingival thickness using i-PRF with microneedle without considering surgical procedures, considering the positive effects of platelet concentrations on revascularization and wound healing in individuals with bone defect, fenestration and gingival thickness which are prone to gingival recession .

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Periodontoclasia Gingiva; Injury Condition Blood Clot Gingiva Disorder

Interventions

I-PRFOTHER

Venous blood will be taken from the patient every session and I-PRF will be created in the centrifuge.I-PRF injected on one side of bilateral thin gingival thickness.Microneedle application plus I-PRF injected on the other side in patients with bilateral region with thin gingival phenotype.Apply once a week and one month after the end of the injections, the patient will be called to the control.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Never smokers * Had no history of systemic disease * Aged ≥18 years old Exclusion Criteria: * Patients with a history of diabetes mellitus or systemic disease * Patients who were under any medication that was known to influence periodontal tissues * Patients with hormonal changes such as pregnancy or lactation * Toothless individuals * Patients who were clotting disorders

Locations (1)

Zeliha Betül ÖZSAĞIR

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

Gingival thickness (mm)

Change in clinical measures of gingival thickness

Time frame: 2 months