Fermented and Fiber-rich Food (FeFiFo) Study

Inclusion Criteria: * 18 and older, both genders, all ethnic backgrounds * Healthy subjects willing and able to provide blood, as well as stool specimens * Able to provide signed and dated informed consent. Exclusion Criteria: * Body Mass Index higher than 40. * Vital signs outside of acceptable range at Screening Visit, i.e., blood pressure greater than 160/100, oral temperature greater than 100 degrees F, pulse greater than 100. * Use of any of the following drugs within the last 6 months: 1. systemic antibiotics, antifungals, antivirals or antiparasitics (intravenous, intramuscular, or oral); 2. oral, intravenous, intramuscular, nasal or inhaled corticosteroids; 3. cytokines; 4. methotrexate or immunosuppressive cytotoxic agents; 5. large doses of commercial probiotics consumed (greater than or equal to 10e8 cfu or organisms per day) - includes tablets, capsules, lozenges, chewing gum or powders in which probiotic is a primary component. 6. consumption of \> 20 g fiber/day and \> 7 servings of fermented foods per week. * Acute disease at the time of enrollment (defer sampling until subject recovers). Acute disease is defined as the presence of a moderate or severe illness with or without fever. * Chronic, clinically significant (unresolved, requiring on-going medical management or medication) pulmonary, cardiovascular, gastrointestinal, hepatic or renal functional abnormality, as determined by medical history or physical examination. * History of cancer except for squamous or basal cell carcinomas of the skin that have been medically managed by local excision. * Unstable dietary history as defined by major changes in diet during the previous month, where the subject has eliminated or significantly increased a major food group in the diet. * Recent history of chronic alcohol consumption defined as more than five 1.5-ounce servings of 80 proof distilled spirits, five 12-ounce servings of beer or five 5-ounce servings of wine per day. * Positive test for HIV, HBV or HCV. * Any confirmed or suspected condition/state of immunosuppression or immunodeficiency ( primary or acquired) including HIV infection. * Major surgery of the GI tract, with the exception of cholecystectomy and appendectomy, in the past five years. Any major bowel resection at any time. * History of active uncontrolled gastrointestinal disorders or diseases including: 1. inflammatory bowel disease (IBD) including ulcerative colitis (mild-moderate-severe), Crohn's disease (mild-moderate-severe), or indeterminate colitis; 2. irritable bowel syndrome (IBS) (moderate-severe); 3. persistent, infectious gastroenteritis, colitis or gastritis, persistent or chronic diarrhea of unknown etiology, Clostridium difficile infection (recurrent) or Helicobacter pylori infection (untreated); 4. chronic constipation. Female who is pregnant or lactating.