Admission of Adult-onset Still Disease Patients in the ICU

Central Hospital, Nancy, France45 enrolled

Overview

Since its first description in 1971, diagnosing adult-onset Still's disease (AOSD), a rare multisystemic disorder considered as a multigenic autoinflammatory syndrome, remains challenging. Rarely, AOSD may present severe systemic manifestations and require intensive care. The main purpose of the Stil ICU study is to make the first description of the epidemiology of critically ill AOSD patients. The investigators will use a retrospective cohort study design with dual recruitment strategies: (1) via the AOSD referral centres network and (2) via a French academic medical ICU network.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Adult-Onset Still Disease Critically Ill

Interventions

data collectionOTHER

biological, administrative, clinical, outcome date

Eligibility

Outcomes

Primary Outcomes

number of patients

Number of patients fulfilling the inclusion criteria

Time frame: At inclusion

Secondary Outcomes

APACHE II

Acute Physiologic Assessment and Chronic Health Evaluation II

Time frame: 24hour after ICU admission

Mortality

Kaplan Meier

Time frame: through study completion, maximum 17,5 years after admission

Number of rehospitalisation in ICU

need for critical care after the first hospitalisation in ICU

Time frame: through study completion, maximum 17,5 years after admission

number of hospitalisation in internal medicine ward

number of hospitalisation in internal medicine ward after the first ICU stay

Time frame: through study completion, maximum 17,5 years after admission

recurrent relapses

number of recurrent flares after the first hospitalisation in ICU

Time frame: through study completion, maximum 17,5 years after admission

Admission of Adult-onset Still Disease Patients in the ICU

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes