Efficacy and Tolerance Evaluation of a "Revitalizing" Face Treatment

Derming SRL22 enrolled

Overview

Efficacy and Tolerance Evaluation of a"revitalizing" face treatment consisting of a day and a night cream

Aim of the study was to evaluate clinically and by non-invasive instrumental evaluations the activity of a "revitalizing" face treatment consisting of a day and a night cream, applied for an uninterrupted period of 3 months, by female volunteers, aged 35-60 years, with aging/photo aging of moderate grade.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Face Aging/Photo Aging of Moderate Grade

Interventions

Nutriage SPF 30 day cream and Nutriage night cream (Difa Cooper S.p.a, Italy)OTHER

A fixed quantity of both cosmetic products was applied for an uninterrupted period of 3 months, on the face included the submental area (day cream at the morning and the night cream at the evening), preferentially always at the same hour, with a mild massage

Eligibility

Sex: FEMALEMin age: 35 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * female sex, * age 35-60 years, * Caucasian subjects, * presence of moderate face ritidosis, * agreeing to present at each study visit without make-up, * accepting to follow the instructions received by the investigator, * accepting to not change their habits regarding food, physical activity, face cleansing and make- up use, * agreeing not to apply or take any product or use face massages or other means known to improve skin wrinkle and skin qualities during the entire duration of the study, * accepting not to expose their face to strong UV irradiation (UV session, or sun bathes), during the entire duration of the study, * no participation in a similar study currently or during the previous 3 months * accepting to sign the Informed consent form. Exclusion Criteria: * Pregnancy, * lactation, * sensitivity to the test products or their ingredients (to be assessed by the investigator during the baseline visit), * subjects whose insufficient adhesion to the study protocol is foreseeable. * presence of cutaneous disease on the tested area as lesions, scars, malformations, * recurrent facial/labial herpes, * clinical and significant skin condition on the test area (e.g. active eczema, dermatitis, psoriasis etc.). * endocrine disease, * hepatic disorder, * renal disorder, * cardiac disorder, * pulmonary disease, * cancer, * neurological or psychological disease, * inflammatory/immunosuppressive disease, * drug allergy. * anti-inflammatory drugs, anti-histaminic, topic (application on the face) and systemic corticosteroids, narcotic, antidepressant, immunosuppressive drugs (with the except of hormonal treatment starting more than 1 year ago), * using of drugs or dietary supplements able to influence the test results in the investigator opinion.

Locations (1)

DERMING

Monza, Monza-brianza, Italy

Outcomes

Primary Outcomes

Change of wrinkles grade, around the eyes (Crow's feet)

Variation of wrinkles grade from baseline of the Glogau's reference photographic scale (visual score from 1-4) where: * Type 1: early wrinkles * Type 2: wrinkle in motion * Type 3: wrinkles at rest * Type 4: Only wrinkles