Hydrating Efficacy and Tolerance Evaluation of a Face Cream

Inclusion Criteria: * both sexes, * age 45-60 years, * caucasian subjects, * agreeing to present at each study visit without make-up, * accepting to follow the instructions received by the investigator, * accepting to not change their habits regarding food, physical activity, face cleansing and make- up use, * agreeing not to apply or take any product or use face massages or other means known to improve skin wrinkle and skin qualities during the entire duration of the study, * accepting not to expose their face to strong UV irradiation (UV session, or sun bathes), during the entire duration of the study, * no participation in a similar study currently or during the previous 3 months * accepting to sign the Informed consent form. Exclusion Criteria: * Pregnancy (only for female subjects), * lactation (only for female subjects), * sensitivity to the test product or its ingredients (to be assessed by the investigator during the baseline visit), * subjects whose insufficient adhesion to the study protocol is foreseeable. * presence of cutaneous disease on the tested area as lesions, scars, malformations, * recurrent facial/labial herpes, * clinical and significant skin condition on the test area (e.g. active eczema, dermatitis, psoriasis etc.). * endocrine disease, * hepatic disorder, * renal disorder, * cardiac disorder, * pulmonary disease, * cancer, * neurological or psychological disease, * inflammatory/immunosuppressive disease, * drug allergy. * anti-inflammatory drugs, anti-histaminic, topic (application on the face) and systemic corticosteroids, narcotic, antidepressant, immunosuppressive drugs (with the except of hormonal treatment starting more than 1 year ago), * using of drugs or dietary supplements able to influence the test results in the investigator opinion.