Main proposed benefit of sleeve gastrectomy is loss of ghrelin secreting tissue. Some studies express that ghrelin augment pancreatic regeneration. Therefore we hypothesized that with sleeve gastrectomy it may result with pancreatic insufficiency.
Mechanism of weight loss differs in bariatric surgery according to type of surgery. With sleeve gastrectomy which has restrictive mechanism, ghrelin excretion decreases, and this condition is attributed as an additional mechanism in weight loss. Ghrelin effects pancreatic regeneration, and loss of ghrelin may result with pancreatic insufficiency. Therefore we aimed to deteremine this association.
Study Type
OBSERVATIONAL
Enrollment
50
Preoperative enzyme test before and after sleeve gastrectomy. Sleeve Gastrectomy will be performed. Preoperative (in one month) and Postoperative (after 3 months) pancreatic enzyme sufficiency (with steatocrit or fecal elastase) will be compared.
Umraniye Education and Research Hospital
Istanbul, Ümraniye, Turkey (Türkiye)
RECRUITINGPancreatic excorine enzyme difference
Effect of operation on pancreatic excorine enzyme
Time frame: post operative 3 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.