Effect of Dietary Sodium and Potassium Citrate on Renal Mineral Handling

N/ATerminatedNCT03281928

University of Chicago30 enrolled

Overview

This study intends to characterize the affect of sodium and potassium citrate in the diet on renal function.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

DOUBLE

Enrollment

Conditions

Kidney Stone

Interventions

Sodium and Potassium CitrateDIETARY_SUPPLEMENT

Sodium and potassium citrate levels will be altered in diet and renal mineral handling will be measured as compared to placebo.

PlaceboDIETARY_SUPPLEMENT

Sodium without Potassium Citrate

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * age 18 - 70, approximately equal numbers of men and women * studied by endoscopy with complete papillary mapping and grading * stone formers Exclusion Criteria: * Patients with primary renal diseases or renal impairment (eGFR \< 90), or medical conditions such as diabetes, or systemic diseases or medications that alter calcium metabolism * Patients with known bladder voiding problems

Locations (1)

University of Chicago Medical Center

Chicago, Illinois, United States

Outcomes

Primary Outcomes

Urine Calcium levels

Amount of calcium in the urine will be measured

Time frame: 10 days

Data from ClinicalTrials.gov

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