Multicenter Study to Evaluate the Procedural Safety and Efficacy of ELCA in CAD

Inclusion Criteria: * Have at least one severely stenotic lesion (greater than or equal to 80% diameter stenosis as assessed by visual estimation) * Haemodynamically stable patients coming to the site for cardiac catheterization and angiography for various indications and who fulfill all the following criteria: * Have no clinically significant cardiac arrhythmias, based on ECG results * Have no evidence of valvular pathology, based on echocardiogram results * Have ≥30% left ventricular ejection fraction (LVEF), based on echocardiogram results. * Angiographic evidence of calcification or a chronic total occlusion * Vessel reference diameter greater than or equal to 2.0 mm * Patient is willing and able to comply with study requirements * Women of child bearing potential, willing to use at least two methods of contraception Exclusion Criteria: * Evidence of acute coronary syndrome within 3 months prior to index procedure * Evidence of acute ischemic events * Cardiogenic and non-cardiogenic shock * Active bleeding or coagulopathy * Previous coronary angioplasty within 6 months of the index procedure * Patients participating in trial for another investigational device/medicine within 1 month prior to enrolment in this study * Acute or Chronic renal failure, Impaired renal function (serum creatinine \> 2.5 mg/dl or 221 umol/l) determined within 72 hours prior to index procedure. * Known allergies to the following: Aspirin, Clopidogrel or Ticlopidine, Heparin, Sirolimus or its derivatives, contrast agent (that cannot be adequately pre-medicated), or any metal * Planned surgery within 6 months of enrollment in this study * Life expectancy less than 6 months * Patients known to be suffering from substance abuse (alcohol or drug) * Patients with any other significant co-morbid illness which in the opinion of the investigator is not conducive of inclusion in the study. * Known or suspected Pregnancy * Patients not willing to provide written informed consent * In the investigators opinion subjects will not be able to comply with the follow-up requirements.