The Impact of Misclassification of Obesity by Body Mass Index on Mortality in Patients With Chronic Kidney Disease

Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation326 enrolled

Overview

Unlike the general population, a higher body mass index (BMI) is associated with greater survival among patients with chronic kidney disease (CKD). However, obesity is defined as excess body fat that associated with clearly elevated health risks according to the World Health Organization. In addition, muscle wasting is prevalent among CKD subjects. Thus, we hypothesized that different definition of obesity, based on BMI or body fat percentage, might have different impact on clinical outcomes among CKD population.

Study Type

OBSERVATIONAL

Enrollment

326

Conditions

Chronic Kidney Diseases Obesity

Interventions

No interventionOTHER

No intervention

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects with non-dialysis CKD defined as estimated glomerular filtration rate (eGFR) \<60 ml/min/1.73 m2 Exclusion Criteria: * subjects with liver cirrhosis * subjects with malignancy * subjects with an acute cardiovascular event within the 3 months before screening for inclusion * amputee * pregnancy * subjects with pacemaker * subjects with metallic implant

Outcomes

Primary Outcomes

all-cause mortality

Time frame: medium follow up 4.9 years