This project aims to leverage existing data from a large observational prospective study on dementia, the Three-City study, to investigate the relationship between intakes of polyphenols and the risk to develop dementia in the 12 years following dietary assessment.
The study sample includes 1,329 subjects followed for up to 12 years fro dementia after dietary assessment. The aim is to identify a pattern of polyphenol intake (based on 26 flavonoid and non-flavonoid polyphenol subclasses ascertained using a 24-hour dietary recall) associated with the risk of dementia and AD over 12 years in the 3C Bordeaux cohort.
Study Type
OBSERVATIONAL
Enrollment
1,329
Statistical association between adherence to a pattern of polyphenol intake and the risk to develop dementia and Alzheimer's disease over 12 years
incidence of dementia
incident cases of dementia diagnosed by the expert committee of neurologists at follow-up visits
Time frame: 12 years
incidence of Alzheimer's disease
dementia with probable or possible Alzheimer etiology
Time frame: 12 years
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