Since 1991, idiopathic macular holes (MH) can benefit from an effective treatment initially involving pars plana vitrectomy, stripping of epiretinal membranes and intraocular gas tamponade followed by facedown positioning. The initial 58% success rate has further increased to 85-100% with internal limiting membrane (ILM) peeling. However, complete ILM removal has been shown to lead to anatomic changes causing the retina to have the appearance of a dissociated optic nerve fiber layer (DONFL). Moreover, it has been associated with decreased retinal sensitivity that may cause visual discomfort despite good visual acuity. Nawrocki et al. recently suggested to reduce the area of peeled ILM (temporal inverted ILM flap technique) in order to minimize iatrogenic trauma while maintaining satisfactory surgical outcomes. The aim of this study is to compare the incidence of DONFL appearance and retinal sensitivity after macular hole surgery in eyes that underwent temporal inverted ILM flap technique and eyes that had complete ILM peeling
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
130
Vitrectomy, temporal inverted or complete ILM peeling and gas tamponade
Brabois Hospital
Vandœuvre-lès-Nancy, France
Number of dimples on optical coherence tomography
Incidence of DONFL appearance
Time frame: 3 months after surgery
Retinal sensitivity on microperimetry testing (decibel)
Time frame: 3 months after surgery
Macular hole closure rate on optical coherence tomography
Time frame: 3 months after surgery
Visual acuity (Logarithm of the Minimum Angle of Resolution)
Time frame: 3 months after surgery
Ellipsoide zone defect on optical coherence tomography
Time frame: 3 months after surgery
External limiting membrane defect on optical coherence tomography
Time frame: 3 months after surgery
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