Improving Decisions About CPR

Ottawa Hospital Research Institute200 enrolled

Overview

Objective The primary objective is to evaluate the efficacy of a multi-faceted, clinical decision support intervention aimed at improving the quality of decisions about Cardio Pulmonary Resuscitation (CPR) for seriously ill, elderly patients in hospital. The hypothesis is that fewer patients in the intervention group will have a documented order for CPR and they will have greater satisfaction with decision making about CPR than patients in the control group.

Methodological Approach The study will be a randomized controlled trial comparing a multi-faceted decision support intervention to usual care for hospitalized patients. The primary objective of this study is to determine if our multifaceted intervention changes decisions about CPR. The components of the multifaceted intervention have already been evaluated for feasibility and acceptability in the hospital setting. The intervention has two parts: the first is a values clarification exercise, and the second part is a CPR video decision aid that explains the risks and benefits of CPR as well as the reasons a patient may choose to receive CPR or not. From previous research it is known that many hospitalized patients have prescribed orders for CPR despite expressing a preference not to have CPR when asked. Furthermore patients often have expressed values that are not concordant with their expressed wishes regarding resuscitation. Therefore it is hypothesized that fewer patients in the intervention group will have a documented order for CPR and they will have greater satisfaction with decision making about CPR than patients in the control group. We will conduct sensitivity analyses to investigate whether the intervention is more effective among patients who remain in hospital longer after enrollment. We will measure the intervention effect among patients who remained in hospital for fewer than three days after enrollment, among patients who were in hospital for 3-7 days after enrollment, and among patients who remained in hospital for longer than 7 days post-enrollment.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

200

Conditions

CPR Decision-Making

Interventions

Decision SupportBEHAVIORAL

A two-part intervention to help patients make better decisions about CPR

Eligibility

Sex: ALLMin age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Eligible to receive CPR 2. Satisfying at least one of the following criteria groups 1. 55 years of age or older with one or more of the following diagnoses: * Chronic obstructive lung disease (2 of the 3 of: baseline PaCO2 of \> 45 torr, cor pulmonale; respiratory failure episode within the preceding year; forced expiratory volume in 1 sec \<0.5 L) * Congestive heart failure (New York Heart Association class IV symptoms and left ventricular ejection fraction \< 25%) * Cirrhosis (confirmed by imaging studies or documentation of esophageal varices and one of three conditions; hepatic coma, child's class C liver disease, or child's class B liver disease with gastrointestinal bleeding) * Cancer (metastatic cancer or stage IV lymphoma) * End-stage dementia (inability to perform all ADLs, mutism or minimal verbal output secondary to dementia, bed-bound state prior to acute illness). 2. 80 years of age or older and admitted to hospital from the community for an acute medical or surgical condition. 3. If none of the above criteria are met, any patient whose death within the next 6 months would not surprise any member of their care team. 4. At least 55 years old and predicted risk of death in the next 12 months of \>=10% as calculated with the HOMR Now! Score Exclusion Criteria: * Patients or SDMs who do not speak English. * Patients or SDMs who do not provide informed consent.

Locations (2)

The Ottawa Hospital General Campus

Ottawa, Ontario, Canada

Ottawa Hospital Civic Campus

Ottawa, Ontario, Canada

Outcomes

Primary Outcomes

CPR Orders

The proportion of patients with an order for CPR in the medical record

Time frame: 14 days post enrollment

Secondary Outcomes

Patient/Substitute Decision Maker (SDM) satisfaction with decision-making

Decision-making domain of the Canadian Health Care Evaluation Project (CANHELP) questionnaire

Time frame: Immediately after intervention, or enrollment for control group

Decisional Conflict

Measured using a modified version of the Decisional Conflict Scale

Time frame: Immediately after intervention, or enrollment for control group

Health Resource Usage

Case costing system at the Ottawa Hospital data warehouse used to measure total cost of hospital care for patients (direct and indirect)

Time frame: From enrolment to 1 year after enrollment.

Number of documented goals of care conversations

Count of documented goals of care conversations, defined as "a conversation that addressed at least one of the following domains: patient values and goals; prognosis or illness understanding; end-of-life care planning; or code status (that is, whether or not a patient has requested resuscitation in the event of a Code Blue) or desire for other life-sustaining treatments or procedures." (Lakin et al. Health Affairs 36, no.7 (2017):1258-1264). We will report the presence or absence of any goals of care conversation, as well as the mean number of conversations in each group.

Time frame: Between study enrollment and up to 14 days post enrollment

Quality of documented goals of care conversations

Mean quality score for the first instance of a goals of care conversation following study enrollment. Quality assessed using the scale developed for Lakin et al. 2017. This scale has a maximum score of 17 and a minimum score of 1.

Data from ClinicalTrials.gov

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