Brain Markers of Suicide Risk and Psychological Pain in Elderly Depressed Patients

Inclusion Criteria: * The patient must have given their free and informed consent and signed the consent form * be a member or beneficiary of a health insurance plan * aged 60 years-old or more * must be right-handed * with a diagnosis of a current major depressive episode of moderate to severe severity according to diagnostic criteria. * with or without a personal history of attempted suicide during life * hospitalized or followed by a consultant in the department of Psychiatry of Nîmes University Hospital or in the Sophoras private clinic Exclusion Criteria: * The subject is participating in an interventional study, or is in a period of exclusion determined by a previous study * under safeguard of justice * refuses to sign the consent * It is impossible to give the subject informed information * Current psychotic symptoms. * Bipolar disorder. * The subject presents an acute somatic decompensation incompatible with the realization of this study. * The patient presents a mental confusion or a known Mini Mental State Examination score \<24. * Central neurological disease known in particular degenerative pathology, severe cranial trauma and severe cerebrovascular disease. * Schizophrenia and other known psychotic disorders. * Electroconvulsive therapy in the 12 months prior to study * Inability to perform neuropsychological tests because of a language problem, poor understanding, a major tremor, inability to sit still, a major sight problem that cannot be corrected, or other severe cognitive impairment * Contra-indication to magnetic resonance imaging (MRI): ferromagnetic implant in the body, piercing, claustrophobia, inability to remain elongated for 45 minutes.