ToT and Estrogen in Postmenopausal Females

Kasr El Aini Hospital210 enrolled

Overview

To compare the subjective and objective outcomes of TVT-O procedure alone versus the same procedure followed by the use of premarin vaginal cream for 3 months in postmenopausal female with genuine stress incontinence.

a randomized controlled trial comparing the effect of using local estrogen cream after tot in postmenopausal female

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

210

Conditions

Stress Urinary Incontinence Postmenopausal Disorder

Interventions

TVT-OPROCEDURE

transobturator tape has been applied to all the patients in the study,and local estrogen vaginal cream is only applied to patients in group A

Eligibility

Sex: FEMALEMin age: 49 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: -menopause patients included in group A should have: no history of breast cancer, ovarian cancer or uterine cancer No history of blood clots or thromboembolism No history of heart disease or stroke No history liver disease. Endometrial thickness less than 5mm Have a normal mammogram Exclusion Criteria: * presence of urge or mixed incontinence .

Locations (1)

Kasr El Ainiy Hospital

Cairo, Egypt

Outcomes

Primary Outcomes

outcome of the surgery

clinical and urodynamic test improvment of the stress incontinence

Time frame: immediately after surgery

outcome of the surgery

clinical and urodynamic test improvment of the stress incontinence

Time frame: 3 months after surgery